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Clinical Trial News

This section provides information about recently completed clinical trials. If you cannot find information about a particular clinical trial, you should note that results may not be available even after the trial ends. Some trials end before completion and results are never published.

New data presented at AD/PD 2023 show IONIS-MAPT Rx (BIIB080) substantially reduced tau protein in patients with early-stage Alzheimer's disease

CARLSBAD, Calif., March 29, 2023. Ionis Pharmaceuticals, Inc. today reported that its partner Biogen presented new Phase 1b clinical data showing that...

Regeneron and Sonoma Biotherapeutics Announce Collaboration to Discover, Develop and Commercialize Treg Cell Therapies for Autoimmune Diseases

TARRYTOWN, N.Y., and SOUTH SAN FRANCISCO, Calif., March 28, 2023 (GLOBE NEWSWIRE) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sonoma Biotherapeutics...

NIH Researchers Discover New Autoinflammatory Disease, Suggest Target for Potential Treatments

March 28, 2023 -- Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in...

Trial Results for Ovarian Cancer will lead to new Standard of Care

MIAMI BEACH, Fla., March 28, 2023. Mount Sinai Medical Center (MSMC) is pleased to announce the results of a clinical trial led by Brian Slomovitz, MD...

Revolo Biotherapeutics Announces Completion of Phase 2a Trial of ‘1104 in Allergic Disease

NEW ORLEANS and CAMBRIDGE, England, March 27, 2023. Revolo Biotherapeutics (“Revolo Bio” or the “Company”), a company developing...

HIV Can Persist for Years in Myeloid Cells of People on Antiretroviral Therapy

March 27, 2023 -- A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on...

Eplontersen Demonstrated Sustained Benefit in Phase III Trial for Hereditary Transthyretin-Mediated Amyloid Polyneuropathy (ATTRv-PN) Through 66 Weeks

27 March 2023 -- Positive high-level results from the NEURO-TTRansform Phase III trial in patients with hereditary transthyretin-mediated amyloid...

FDA Issues Draft Guidance Aimed at Improving Oncology Clinical Trials for Accelerated Approval

SILVER SPRING, Md., March 24, 2023. Today, the U.S. Food and Drug Administration issued draft guidance, Clinical Trial Considerations to Support Accelerated...

Enrollment Completion for Global, Phase 3b Study of RADICAVA ORS in ALS

JERSEY CITY, N.J., March 23, 2023- Mitsubishi Tanabe Pharma America, Inc. (MTPA) today announced it has completed enrollment for the global, multi-center...

Jacobio announces clinical collaboration to evaluate CD73 monoclonal antibody JAB-BX102 in combination with KEYTRUDA for patients with cancer

BEIJING, SHANGHAI and BOSTON, March 22, 2023. Jacobio Pharma (1167.HK) announced it has entered into a clinical collaboration with Merck & Co., Inc...

Diamond Therapeutics Announces FDA-authorized Clinical Trial of Low-Dose Psilocybin in Collaboration with University of Alabama at Birmingham

TORONTO, March 21, 2023. Diamond Therapeutics Inc. ("Diamond"), a drug development company focused on low-dose psychedelic-derived therapies for use in the...

New Yale study evaluates PAXLOVID's use in Long COVID recovery

NEW HAVEN, Conn., March 21, 2023. Yale School of Medicine announces the initiation of a novel, randomized trial that will test whether receiving...

Astellas Announces Positive Findings from Phase 3 GLOW Trial of Zolbetuximab during March ASCO Plenary Series

TOKYO, March 21, 2023 /PRNewswire/ -- Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., "Astellas") will present detailed results from...

First Subjects Dosed in Phase 1 Clinical Trial of VXX-401, Investigational Anti-PCSK9 Vaccine to Treat Hypercholesterolemia

CAPE CANAVERAL, Fla., March 20, 2023. Vaxxinity, Inc., a U.S. company pioneering the development of a new class of immunotherapeutic vaccines, today announced...

Patritumab Deruxtecan Continues to Show Encouraging Clinical Activity in Distinct Patient Populations with Metastatic Lung and Breast Cancer in Updated Results of Two Early Trials

TOKYO & BASKING RIDGE, N.J.--(BUSINESS WIRE) March 20, 2023 --New data from Daiichi Sankyo’s (TSE: 4568) patritumab deruxtecan (HER3-DXd) from two...

Phase 3 Study Shows XTANDI plus Leuprolide Significantly Improves Metastasis-Free Survival in Men with Non-Metastatic Prostate Cancer

NEW YORK and TOKYO, March 17, 2023. Pfizer Inc. and Astellas Pharma Inc. ("Astellas") today announced positive topline results from the Phase 3 EMBARK trial...

Merck Provides Update from Open-Label Arm of Phase 2 KeyVibe-002 Trial Evaluating MK-7684A, a Coformulation of Vibostolimab and Pembrolizumab, in Previously Treated Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC)

RAHWAY, N.J.--(BUSINESS WIRE) March 16, 2023 -- Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today provided an update on the...

Arbutus Doses First Subject in Phase 1 Clinical Trial with its Oral RNA Destabilizer, AB-161

WARMINSTER, Pa., March 16, 2023.. Arbutus Biopharma Corporation (“Arbutus”), a clinical-stage biopharmaceutical company leveraging its extensive...

Janssen Announces Novel Dengue Antiviral Demonstrates Efficacy in Pre-Clinical Data Published in Nature

BEERSE, BELGIUM, March 15, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) announced today the publication of new data in...

Positive results from a pharmacokinetic study with cobitolimod in patients with moderate to severe ulcerative colitis

STOCKHOLM, March 15, 2023. InDex Pharmaceuticals Holding AB (publ) today announced positive results from a pharmacokinetic (PK) study with cobitolimod in...

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